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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE3B
All Species:
25.15
Human Site:
Y799
Identified Species:
50.3
UniProt:
Q13370
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13370
NP_000913.2
1112
124333
Y799
C
S
N
P
D
E
S
Y
G
C
L
S
S
N
I
Chimpanzee
Pan troglodytes
XP_520783
1141
125048
Y814
Y
N
V
T
D
D
K
Y
G
C
L
S
G
N
I
Rhesus Macaque
Macaca mulatta
XP_001092891
1117
125088
Y799
C
S
I
P
D
E
S
Y
G
C
L
S
S
N
I
Dog
Lupus familis
XP_854529
779
87136
P529
W
N
L
Y
L
S
R
P
E
Y
N
F
L
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q61409
1100
122135
Y775
C
C
I
P
D
M
S
Y
G
C
L
S
S
N
I
Rat
Rattus norvegicus
Q63085
1108
123088
Y781
C
C
I
P
D
K
S
Y
G
C
L
S
S
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518516
340
38206
S90
G
R
V
A
Y
I
S
S
K
S
C
P
I
L
D
Chicken
Gallus gallus
NP_001026353
1105
121291
Y787
C
S
I
T
D
D
S
Y
G
C
L
A
S
N
I
Frog
Xenopus laevis
NP_001088828
985
108702
P735
W
N
L
F
L
S
Q
P
E
Y
N
F
L
S
Y
Zebra Danio
Brachydanio rerio
XP_691883
1107
124050
Y788
S
S
F
Q
D
D
S
Y
G
C
L
A
W
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8I0P7
625
69850
R375
H
D
Y
D
H
P
G
R
T
N
A
F
L
V
Q
Sea Urchin
Strong. purpuratus
XP_793920
1558
171759
Y1162
S
I
S
S
D
S
S
Y
G
I
L
A
G
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42
96.7
60.6
N.A.
81.5
80.6
N.A.
22.4
63.6
59.7
63.2
N.A.
N.A.
N.A.
26.5
28.2
Protein Similarity:
100
58.2
98.2
64.5
N.A.
86.9
86.7
N.A.
26.9
75
70.8
75.5
N.A.
N.A.
N.A.
38.2
41.8
P-Site Identity:
100
53.3
93.3
0
N.A.
80
80
N.A.
6.6
73.3
0
53.3
N.A.
N.A.
N.A.
0
40
P-Site Similarity:
100
66.6
93.3
6.6
N.A.
80
86.6
N.A.
6.6
86.6
13.3
73.3
N.A.
N.A.
N.A.
0
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
0
9
25
0
0
0
% A
% Cys:
42
17
0
0
0
0
0
0
0
59
9
0
0
0
0
% C
% Asp:
0
9
0
9
67
25
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
0
0
0
17
0
0
17
0
0
0
0
0
0
% E
% Phe:
0
0
9
9
0
0
0
0
0
0
0
25
0
0
0
% F
% Gly:
9
0
0
0
0
0
9
0
67
0
0
0
17
0
0
% G
% His:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
34
0
0
9
0
0
0
9
0
0
9
0
50
% I
% Lys:
0
0
0
0
0
9
9
0
9
0
0
0
0
0
0
% K
% Leu:
0
0
17
0
17
0
0
0
0
0
67
0
25
17
9
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
25
9
0
0
0
0
0
0
9
17
0
0
67
9
% N
% Pro:
0
0
0
34
0
9
0
17
0
0
0
9
0
0
0
% P
% Gln:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
9
% Q
% Arg:
0
9
0
0
0
0
9
9
0
0
0
0
0
0
0
% R
% Ser:
17
34
9
9
0
25
67
9
0
9
0
42
42
9
0
% S
% Thr:
0
0
0
17
0
0
0
0
9
0
0
0
0
0
0
% T
% Val:
0
0
17
0
0
0
0
0
0
0
0
0
0
9
9
% V
% Trp:
17
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
9
0
9
9
9
0
0
67
0
17
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _